Medical MCQs

5099 MCQs  (Page 407 of 510)

Which factor of the following contributes to short duration of anesthetic action of single dose thiopental_____________?
A. Rapid biotransformation
B. Rapid accumulation in body fat
C. High lipid solubility
D. Ability to enter and leave brain tissue every rapidly
What is the advantage of sublingual route of administration of drugs_____________?
A. Prevents or bypasses first pass effects
B. Easy to administer
C. Lipid soluble
D. Can be spitted out with signs of toxicity
Drug which crosses placental barrier is____________?
A. Phenytoin
B. Diazepam
C. Corticosteroids
D. All of the above
I.V anesthesia is_________________?
A. Propofol
B. Sevoflurane
C. Flumazanil
D. Naloxane
DOPA and 5-Hydroxytryptophan are clinically important because_____________?
A. They cross blood brain barriers
B. They are acidic precursors of brain amines
C. They act as neuromodulators
D. They are metabolites of various neurogenic amines
The ratio of the median lethal dose of the median effective dose is the_____________?
A. Morbidity index
B. Moratality index
C. Anesthetic ratio
D. Therapeutic index
Km value indicates______________?
A. Purity of enzyme
B. Physiological role
C. Half life enzymes drug complex
D. Affinity
A prodrug is____________?
A. The proto type member of a class of drugs
B. The oldest member of a class of drugs
C. An inactive drug that is transformed in the body to an active metabolite
D. A drug that is stored in body tissues and is then gradually released in the direction